We aim to understand how RNA-level (transcription initiation, splicing, etc) changes in (mostly) human tissues increase proneness to diseases, namely cancer, neurodegenerative disorders and other ageing-related pathologies.

We thereby aim to identify molecular targets for functional exploration in vitro and in vivo. We also combine molecular and clinical information for the unveiling of novel candidate prognostic factors and therapeutic targets. Along the way, we develop some tools for assisting non-computational scientists in their analyses of transcriptomic data. We coordinate BIOMICS, a Twinning project funded by the European Union aiming at "Fostering Excellent Research, Training and Innovation in Biomedical Data Science".