Localização

CEDOC Campus Sant'Ana Pólo de Investigação, NMS, UNL Rua do Instituto Bacteriológico, nº 5 Lab 1.3 1150-082 Lisboa, Portugal
Telefone: +351 218803101 Ext: 27018

Juliane Menezes

Investigador Investigador Auxiliar
Associate Researcher, PhD

As an Associate Researcher at the IBL, CEDOC, I have been working on gene circuits for transcriptional program biosensors that we plan to use for cancer diagnostic and therapeutic purposes.

Graça R, Fernandes R, Alves AC, Menezes J, Romão L, Bourbon M. Characterization of Two Variants at Met 1 of the Human LDLR Gene Encoding the Same Amino Acid but Causing Different Functional Phenotypes. Biomedicines. 2021 Sep 14;9(9):1219.  doi: 10.3390/biomedicines9091219
Herédia FO, Volonté Y, Pereirinha J, Fernandez-Acosta M, Casimiro AP, Belém CG, Viegas F, Tanaka K, Menezes J, et al. The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction. Nat Commun. 2021 Jun 7;12(1):3328.  doi: 10.1038/s41467-021-23218-5.
Costa P, Menezes J, Saramago M, García-Moreno J, Santos H, Gama-Carvalho M, Arraiano C, Viegas S, Romão L. Experimental supporting data on DIS3L2 over nonsense-mediated mRNA decay targets in human cells. Data Brief. 2019 Dec 6;28:104943.  doi: 10.1016/j.dib.2019.104943.
Costa P, Menezes J, Saramago M, García-Moreno J, Santos H, Gama-Carvalho M, Arraiano C, Viegas S, Romão L. A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells. Biochem Biophys Res Commun. 2019 Oct 22;518(4):664-671.  doi: 10.1016/j.bbrc.2019.08.105.
Gomes-Duarte A, Lacerda R, Menezes J, Romão L. eIF3: a factor for human health and disease. RNA Biol. 2018 Jan 2;15(1):26-34.  doi: 10.1080/15476286.2017.1391437.
Menezes J, Ventura C, Costa JM, Parreira E, Romão L, Gonçalves J. PROS1 novel splice-site variant decreases protein S expression in patients from two families with thrombotic disease. Clin. Case Rep. 2017 Nov 3;5(12):2062-2065.  doi: 10.1002/ccr3.1226.
Marques-Ramos A, Candeias MM, Menezes J, Lacerda R, Willcocks M, Teixeira A, Locker N, Romão L. Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition. RNA. 2017 Nov;23(11):1712-1728.  doi: 10.1261/rna.063040.117.
Costa P, Menezes J, Romão L. The role of alternative splicing coupled to nonsense-mediated mRNA decay in human disease. Int J Biochem Cell Biol. 2017 Oct;91(Pt B):168-175.  doi: 10.1016/j.biocel.2017.07.013.
Lacerda R,  Menezes J, Romão L. More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer. Cell Mol Life Sci. 2017 May;74(9):1659-1680.  doi: 10.1007/s00018-016-2428-2.
Menezes J, Cigudosa JC. Chronic neutrophilic leukemia: a clinical perspective. Onco Targets Ther. 2015 Sep 1;8:2383-90.  doi: 10.2147/OTT.S49688.
Salgado RN, Menezes J, Calvente M, Suela J, Acquadro F, Martínez-Laperche C, Flores R; et al. Myeloid neoplasms with der(1)t(1;19) may constitute a specific entity characterized by a cytogenetic biomarker and gene mutations involved in DNA methylation. Leuk Lymphoma. 2014 Nov;55(11):2652-5.
Menezes J, Acquadro F, Wiseman M, Gómez-López G, Salgado RN, Talavera-Casañas JG, Buño I, et al. Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm. Leukemia. 2014 Apr;28(4):823-9.  doi: 10.1038/leu.2013.283.  
Menezes J, Makishima H, Gomez I, Acquadro F, Gómez-López G, Graña O, Dopazo A, et al. CSF3R T618I co-occurs with mutations of splicing and epigenetic genes and with a new PIM3 truncated fusion gene in chronic neutrophilic leukemia. Blood Cancer J. 2013 Nov 8;3(11):e158.  doi: 10.1038/bcj.2013.55.
Menezes J, Salgado RN, Acquadro F, Gómez-López G, Carralero MC, Barroso A, Mercadillo F, et al. ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia. Blood Cancer J. 2013 Nov 8;3(11):e157.  doi: 10.1038/bcj.2013.54.
Rio-Machín A, Menezes J, Maiques-Diaz A, Agirre X, Ferreira BI, Acquadro F, Rodriguez-Perales S, et al. Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22). Haematologica. 2012 Apr;97(4):534-7.  doi: 10.3324/haematol.2011.050567.

2013    Post-Doctoral Fellowship (Fundação para a Ciência e a Tecnologia, Portugal)
2009    PhD Fellowship (Obra Social La Caixa, Spain)
2007    Master Fellowship (Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil)
2004    Undergraduate Fellowship (Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil)

https://www.cienciavitae.pt/portal/1714-0687-B84D