Teses e Dissertações

Lista de teses de doutoramento e dissertações de mestrado apresentadas por ano e área de especialidade/investigação




ALMEIDA, Ana - Screening for retinopathy of prematury: how can we do better?

BRANCO, Patrícia - Peritoneal histomorphology, biomarkers and clinical outcomes in patients with chronic kidney disease on peritoneal dialysis

BRITO, Maria - Cervical squamous cell carcinoma (SCC) and cervical intraepithelial lesions (SILS) in hiv women: contribution of the local immune response (embargo 2 anos - 20.10.2023 a 20.10.2025)

COUTO, Nuno - Tumoral exosomes profile in metastatic pancreatic adenocarcinoma patients during chemotherapy treatment

FERNANDES, João - Social cognition in patients with schizophrenia and autism spectrum disorder

FERREIRA, Alexandre - Improving the quality of colonoscopy 

GOUVEIA, Catarina - Osteoarticular infections in pediatric patients : changes in epidemiology and treatment (embargo 2 anos - 22.06.2023 a 22.06.2025)

LUZ, José - BestFLR. Randomized controlled clinical trial comparing preoperative portal embolization with polyvinyl alcohol particles (PVA) and coils versus N-butyl cyanoacrylate (NBCA)

MARIA, Ana - Accounting for doctors and patients perceptions in telehealth services implementation

PARREIRA, Leonor - A novel simplified approach to radiofrequency catheter ablation of idiopathic ventricular outflow tract premature ventricular contractions: from substrate analysis to results

RAPOSO, Luís - Intracoronary transfer of human Umbilical Cord matrix‐derived Mesenchymal Stem Cells for the preservation of left ventricular function after acute myocardial infarction: assessment of invasive hemodynamic effects and potential underlying mechanisms in a large animal pre-clinical model (embargo 1 ano - 02.06.2023 a 02.06.2024)

REIS, Teresa - Prescription of benzodiazepines by primary health care doctors: characteristics of prescribing trend and implementation of an online program (embargo 2 anos - 24.02.2023 a 24.02.2025)

TELES, Rui - Transcatheter aortic valve implantation (TAVI) a reference model in percutaneous cardiovascular intervention


BOTA, Catarina - Testing the role of asymmetric migratory behaviors found in a novel population of mesendodermal cells (embargo 2 anos - 30.10.2023 a 30.10.2025)

BURRINHA, Tatiana - Lysosome dysfunction, the link between aging and alzheimer’s disease? (embargo 3 anos - 27.01.2023 a 27.01.2026)

COTOVIO, Gonçalo - Interhemispheric imbalance in mood disorders (embargo 3 anos - 24.01.2023 a 24.01.2026)

CORREIA, Maria - Hydroxytyrosol and hypertension associated with chronic intermittent hypoxia: impact and contribution of AhR alternative pathway (embargo)

DELGADO, Raquel - Regulation of survival and death pathways in chronic lymphocytic leukemia (embargo 3 anos - 28.06.2023 a 28.06.2026)

FIALHO, Isabel - A psicoterapia de grupo de orientação grupanalítica : levantamento e caraterização a nível nacional, em meio hospitalar, e avaliação da eficácia em grupos psicoterapêuticos de diferentes dimensões

MADEIRA, Natália - Rethinking memory acquisition: the rules of Memory cooperation and competition (3 anos embargo - 31.05.2023 a 31.05.2026)

SOUSA, Daniela - Human Papillomaviruses in Head and Neck Squamous cell carcinomas: the relevance of HPV16 variants

Ciências da Saúde - especialidade Biomedicina

BRANDÃO, Duarte - A cell-type specific selection system for stem cell therapy (and other) purposes (embargo 3 anos - 30.05.2023 a 30.05.2026)

FERREIRA, Andreia - Modulating membrane traffic regulators to impair breast cancer progression (3 anos embargo - 13.03.2023 a 13.03.2026)

Mecanismos da Doença e Medicina Regenerativa (ProRegeM)

CASTANHEIRA, Pedro - The role of rab11a and rab11b in breast cancer progression (embargo 3 anos - 20.04.2023 a 20.04.2026)

LOPES, João - The role of Cerl2 in cardiomyocyte differentiation and heart regeneration (embargo 2 anos - 11.04.2023 a 11.04.2025)

MEYER, Catarina - The mechanism of LAMP2A-mediated exosome biogenesis and their role in intercellular communication

MIRFAKHAR, Farzaneh - Investigating the association of endocytic trafficking regulator CD2AP gene variant K633R and the risk of developing Alzheimer's disease (embargo 3 anos - 01.02.2023 a 01.02.2026)

PESTANA, Sara - Testing the role of extracellular vesicles in early left right patterning


Envelhecimento e Doenças Crónicas

KUBASOVA, Nadiya - Epigenetics and genetics of hematopoietic stem cells heterogeneity

NETO, Matilde - Molecular mechanisms of melanin internalization and processing in keratinocytes (embargo de 3 anos - 29.06.2023 a 29.06.2026)

RODRIGUES, Joana - Dissecting the role of ral gtpase in neuronal and glial structure and function

SILVA, Daniela - The role of toll-like receptors expressing t cells in autoimmunity (embargo de 3 anos - 05.04.2023 a 05.04.2026)


Bioquímica para a Saúde

BARRADAS, Bárbara - Protein Glycosylation in Cancer Drug Resistance (embargo de 3 anos - 15.03.2023 a 15.03.2026)

CAÇÃO, Marta - Evaluating the protective effect of beries-derived poliphenol metabolites in mouse retina degeneration (embargo de 3 anos - 27.03.2023 a 27.03.2026)

CHANDE, Andreia - Alternative splicing variants in breast cancer

CRISPIM, Daniel - The role of the cytochrome P450-enzyme complex protein factors and other oxidoreductases in the mechanisnms of acquired cancer drug resistance (embargo 2 anos)

FRANCISCO, Mafalda - Phenylalanine hydroxylase (pah) enzymosomes: development of a nanosystem for enzyme substitution/replacement therapies (embargo de 2 anos - 04.04.2023 a 04.04.2025)

PEDRO, Margarida - Development of a screening pipeline to identify modulators of NRF2 activity (3 anos embargo)

RAMOS, Carolina - The role of extracellular vesicles in chemotherapy resistance mediated by the breast cancer-liver axis (embargo 2 anos)

SALVADO, Beatriz - Beating primary ciliary dyskinesia (embargo 2 anos)

SESIFREDO, Isabel - Role of lysosome exocytosis in breast cancer progression (embargo 3 anos)


Gestão da Investigação Clínica

COSTA, Carlota - Gestão do centro de investigação : promoção e organização de investigação interna

EÇA, Rita - Digitalização de um centro de investigação clínica : desenho de um plano estratégico trabalho de projeto / Rita Horta Osório da Cunha de Eça 

PICADO, Mariana - A fadiga em doentes com cancro do pulmão sob imunoterapia FADIMUN: estudo observacional prospetivo (1 ano embargo)


Investigação Biomédica (NBR)

ALVES, Beatriz - VIP neuroepithelial circuit in immunity and metabolism (embargo 3 anos)

COELHO, Pedro - Self-paced VS cued movement initiation : characterising behaviour and underlying neural circuits (embargo)

FERRAZ, Luís - Exosomes in transcellular proteostasis and Age-Related Macular Degeneration

FERREIRA, Bárbara - The role of glucagon : GCGR axis in pancreatic neuroendocrine

GRENHAS, Maria - Comparative analysis of size-exclusion chromatography and ultracentrifugation for efficient isolation of extracellular vesicles in Multiple Myeloma (embargo)

LEÃO, José - Modulation of adenosinergic system as a therapeutic target for dysmetabolism  

OLIVEIRA, Inês - Screening innate immunotherapy strategies in zebrafish xenograft models

PACHECO, Maria - Developing 3D in vitro models of basal cell carcinoma (embargo)

PEREIRA, Pedro - Extracellular vesicles: communication agents in prediabetes (embargo 1 ano)

QUADRADO, Carolina - Nutrient postingestive signalling: the asymmetry of the response of dopaminergic neuronal circuits (embargo 3 anos - 09.03.2023 a 09.03.2026)

REIS, Fábio - Epithelial to mesenchymal transition pathway in pituitary endocrine tumours

ROSADO, Pedro - Study of the impact of the IL-7R on non-small cell lung cancer (embargo)

SALDANHA, Inês - Extracellular Vesicles as biomarkers of hepatic metastasis in pancreatic cancer patients (embargo)


Nutrição Humana e Metabolismo

BAETA, Inês - Catering for athletes: food and nutritional considerations at international athletics championships (embargo 3 anos - 08.11.2023 a 08.11.2026)

CALAFATE, Catarina - Evaluation of mental health, cognitive function and quality of life of breast cancer patients and the link with gut microbiota : a preliminary study

CAMPOS, Teresa - The link between breast cancer treatment toxicity and gut microbiota: a preliminary study (embargo 3 anos - 17.07.2023 a 17.07.2026)

CAPITÃO, Carolina - The relationship between tumor metabolic activity and body composition changes in patients with cancer (3 anos embargo)

CARREIRA, Eduarda - The effects of a Mediterranean-style diet in heart disease patients running a cardiac rehabilitation program (embargo 3 anos - 29.11.2023 a 29.11.2026)

FIGUEIRA, Carina - Effects of a weight loss program on cardiovascular risk in adults with obesity: the WLM3P study 

FONSECA, Gisela - Efeito metabólico de um pequeno-almoço rápido e nutricionalmente equilibrado, desenvolvido para colmatar as necessidades da geração Y : estudo clínico aleatorizado e cruzado (1 ano embargo)

FREITAS, Mariana - O efeito de uma dieta anti-inflamatória na atividade da doença e na qualidade de vida de pacientes com artrite reumatóide: ensaio clínico randomizado controlado paralelo (embargo 1 ano)

GAMA, Maria - Impact on diet quality and dietary burden of sapropterin dihydrochloride use in children with phenylketonuria : a 6 months follow-up report (embargo)

HASSAN, Mihabd - Role of the level of micronutrients (iron, zinc and vitamin D) in developing febrile convulsion in children under six years old (embargo 3 anos)

HENRIQUES, Beatriz - Impacto da ingestão de uma infusão de funcho pelas mães na cólica infantil em bebés amamentados com leite materno (embargo 2 anos)

LEMOS, Maria - Urinary biomarkers of biofortified beef in healthy women explored by untargeted metabolomics

PERES, Maria - Biochemical and anthropometric outcomes of patients with paediatric heterozygous familial hypercholesterolemia after COVID-19 pandemic lockdowns (embargo 3 anos)

PISCO, Alexandra - Effects of a weight loss program on body composition in adults with obesiy: the WLM3P study

RELVA, Bárbara - Caracterização das alterações metabólicas que ocorrem durante uma dieta hipocalórica de 8 semanas e a sua relação com a eficiência da perda de peso

RIBEIRO, Laila - Avaliação da exposição in utero a contaminantes ambientais em recém-nascidos prematuros (embargo 1 ano - 09.01.2023 a 09.01.2024)

RODRIGUES, Diana - Microspa – gut microbiota and axial spondyloarthritis: the impact on anti-tnf therapy

SOUSA, Catarina - Avaliação da exposição gestacional a metais pesados e a sua associação com o estado de saúde da mulher grávida & outcomes à nascença (embargo 2 anos - 22.09.2023 a 22.09.2025)

SILVA, Rita - BIOMEQUIZ: validation of a food questionnaire to select stool donors (embargo 3 anos - 13.07.2023 a 13.07.2026)

VEIGA, Sofia - Levels of essential and toxic metals in adults with obesity undergoing a weight loss intervention: is there a link with meta-inflammation? (embargo 1 ano - 21.07.2023 a 21.07.2024)

VIDINHA, Duarte - The effects of a school-based intervention on the dietary quality of mid-morning snacks in second grade Azorean children (embargo 1 ano - 24.07.2023 a 24.07.2024)


Saúde Mental nos Cuidados Primários

DUTRA, Filipa - Parenting styles in victims of bullying in childhood and adolescence

RAMOS, Laura - PTSD occurrence and management strategies during the COVID-19 pandemic

Medicina - Investigação Clínica

ALMEIDA, Ana - Screening for retinopathy of prematury: how can we do better? (embargo 2 anos - 04.02.2022 a 04.02.2024)

BALSINHA, Maria - Users and health professionals' perspectives regarding Portuguese primary care services: a focus on dementia (embargo 1 ano - 21.03.2022 a 21.03.2023)

COELHO, Ana - Renal recovery after an episode of acute kidney injury

FERREIRA, Ana - Bone-derived hormones, bone disorders and cardiovascular disease in kidney transplanted patients

FERREIRA, Bruna - The role of extracellular vesiclesin multiple myeloma

MARTO, Natália - In vivo phenotyping of sultia enzymes in man implications for precision medicine

NEVES, Marisa - The role of high-density lipoproteins in the activation of T lymphocytes and regulation of immune response

OURÔ, Susana - Biological and surgical determinants in the treatment of rectal cancer 

ROSA, Sílvia - Microcirculation dysfunction in hypertrophic cardiomyopathy

SILVA, Tiago - Circulating micro-rna profiles according to atherosclerotic disease expression : a contribute to phenotype characterization and insights into pathophysiology


Medicina - Biomedicina

BORBINHA, Jorge - The effects of metabolic reprogramming during zebrafish tissue regeneration (embargo 3 anos - 07.12.2022 a 07.12.2025)

LOPES, Liliana - Molecular mechanisms of melanin secretion by melanocytes and processing within keratinocytes (embargo 3 anos - 21.12.2022 a 21.12.2025)

MATIAS, Ana - Dissecting the differential molecular signature in patients From african-origin with triple-negative breast cancer (embargo 2 anos - 28.04.2022 a 28.04.2024)

SOUSA, Marcelo - Substantia Nigra in Parkinson’s disease: exploring the encoding of movement kinematics by Dopaminergic Neurons (embargo 2 anos - 25.02.2022 a 25.02.2024)


Mecanismos de Doença e Medicina Regenerativa

MARQUES, Graça - Characterization of novel factors regulating neural stem cell proliferation, temporal fate and neuronal diversity (embargo 3 anos - 29.04.2022 a 29.04.2025)

MONTEIRO, Ana - Underlying role of glycation in the pathogenesis of Parkinson’s disease (embargo 3 anos - 30.11.2022 a 30.11.2025)

PINA, Ana F. - Non-communicable diseases stratification and integration: a clinical approach (embargo 3 anos - 13.09.2022 a 13.09.2025)

RODRIGUES, Cátia - Neuronal and glial growth and development: dissecting the role of RalA and exocyst in  Drosophila peripheral nervous system (embargo 2 anos - 09.04.2022 a 09.04.2024)

Saúde Pública Global

MARQUES, Maria - Factors influencing the quality of relationship in dementia: a mixed-methods approach (embargo 3 anos - 07.11.2022 a 07.11.2025)


Bioquímica para a Saúde

BARATA, Isabel - The Role of Progesterone Receptor Membrane Component 1 (PGRMC1) in Cytochromes P450 (CYP)- Mediated Drug Metabolism and its Implication in Chemotherapy Resistance (embargo 2 anos - 06.04.2022 a 06.04.2024)

BENTO, Luís - Anti-inflammatory activity of berries driven polyphenols in zebrafish larvae fed with oxidizedlipids and LPS

COSTA, Ana - Suscetibilidade genética em doentes COVID19 hospitalizados: o caso português (embargo 2 anos - 05.05.2022 a 05.05.2024)

DOMINGUES, Ana - Role of micrornas in cancer drug resistance (embargo 2 anos - 07.02.2022 a 07.02.2024)

DUARTE, Catarina - Role of microRNAs and epigenetics modifications in paclitaxel resistance in a breast cancer cell line model (embargo 2 anos - 28.02.2022 a 28.02.2024)

VALE, Ana - Biological relevance of VUS identified in ATM gene and the role in DNA damage response (embargo 2 anos - 22.04.2022 a 22.04.2024)


Gestão da Investigação Clínica

ABREU, Daniela - Coordenação de estudos clínicos no Centro Hospitalar de Lisboa Ocidental

BARBOSA, Ana - Relatório de estágio em coordenação de investigação clínica na Blueclinical, ltd

BASTOS, Inês - Ensaios clínicos da iniciativa do investigador e descrição do estágio em coordenação de estudos clínicos no IPO Porto

CAETANO, Madalena - Relatório de estágio curricular em coordenação de estudos clínicos no Centro Hospitalar de Lisboa Ocidental, E.P.E.

COELHO, Carolina - Relatório de estágio em coordenação de ensaios clínicos de oncologia

CORREIA, Miguel - Estágio em coordenação de estudos clínicos na CUF Academic Center

COSTA, Mariana - Estágio de coordenação de estudos & atividades de monitorização e start-up de ensaios clínicos na AIDFM-Associação para a Investigação e Desenvolvimento da Faculdade de Medicina 

FIALHO, Helena - Estágio de monitorização de estudos na keypoint, group evidenze

GOEDE, Kay Shawnee - Estágio em gestão e monitorização de estudos clínicos na Novartis Farma

INÁCIO, Ana - Coordenação de estudos clínicos no centro hospitalar lisboa ocidental, E.P.E.

LEMOS, Beatriz - Start-up, monitorização e coordenação de estudos 

PINTO, Catarina - Relatório de estágio curricular em coordenação de estudos clínicos no Lusíadas Knowledge Center

MEDEIROS, João - Relatório de estágio de coordenação em investigação clínica em dois hospitais parceiros da Blueclinical CRP

NETO, Pedro - Relatório de estágio em tarefas regulamentares e de monitorização na W4Research (embargo 1 ano - 14.12.2022 a 14.12.2023)

OLIVEIRA, Madalena - Coordenação de estudos clínicos na Blueclinical

RIBEIRO, Miguel - Relatório de estágio curricular em coordenação de estudos clínicos no Centro Hospitalar Universitário Cova da Beira

SILVÉRIO, Catarina - Start-up e monitorização de estudos clínicos


Investigação Biomédica

ALMEIDA, Vicente - Regulation of γδ17 T cell homeostasis by stress-derived signals (embargo 3 anos - 17.11.2022 a 17.11.2025)

AMORIM, Filipa - Ovarian cancer zebrafish avatar for personalized therapy (embargo 3 anos - 16.11.2022 a 16.11.2025)

AMORIM, Joana - Polymeric nanoparticles for local delivery of multicolor genetic circuits in breast cancer (embargo 3 anos - 02.12.2022 a 02.12.2025)

ANTÓNIO, Patrícia - The effect of sphingosine-1-phosphate in lymphocytes of patients with pancreatic cancer (embargo 2 anos - 14.12.2022 a 14.12.2024)

CAPUCHO, Adriana - The role of carotid body in brain insulin resistance and neurodegeneration

CASTAÑEDA MATIZ, Luisamaria - Unveiling the role of DIPK2B in hematopoietic development and primary immunodeficiencies (embargo 3 anos - 23.11.2022 a 23.11.2025)

CATARINO, Joana - Probing striatal subpopulations in outcome-dependent action control in rats (embargo 1 ano - 14.02.2022 a 14.02.2023)

COELHO, Rita - Characterization of cellular organelles and the endo-lysosomal pathway in choroideremia patient cells (embargo 3 anos - 22.11.2022 a 22.11.2025)

COSTA, Miguel - Biological effect of Type I procollagen carboxyterminal propeptide in breast cancer tumor microenvironment (embargo 2 anos - 12.05.2022 a 12.05.2024)

CUNHA, César - Disclosing lysosomal dysfunction with neuronal aging : a potential mechanism of early synaptic degeneration in alzheimer's (embargo 3 anos - 22.03.2022 a 22.03.2025)

DIAS, Maria - Mechanisms of reinnervation during wound healing: novel roles for epithelial-glial communication (embargo 3 anos - 04.05.2022 a 04.05.2025)

KAMIKI, Jéssica - Mucosal-associated invariante T cells : novel players in pancreatic cancer (embargo 2 anos - 18.01.2022 a 18.01.2024)

LOPES, Francisco - Investigating the role of innate immune memory in microglial-mediated synaptic remodeling (embargo 3 anos - 11.05.2022 a 11.05.2025)

MARQUES, Ana - Contribution of high histone acetylation in memory allocation (embargo 3 anos - 26.04.2022 a 26.04.2025)

MOTA, Sara - A new paradigm to study NF-κB in vivo and the role of dietary phenolic metabolites using drosophila (embargo 3 anos - 10.05.2022 a 10.05.2025)

PACHECO, Rita - Proteomic approach to the caracterization of unknown origin male infertility

PEREIRA, Tiago - Uncovering the mechanism of CD2AP behind Alzheimer’s disease (embargo 3 anos - 23.11.2022 a 23.11.2025

PIRES, Dinis - GLP1 acts on the carotid body to modulate glucose homeostasis and cardiorespiratory responses (embargo 3 anos - 15.12.2022 a 15.12.2025)

SAAB, Maria - Engineered cardiac tissues with improved maturation for regenerative medicine (embargo 2 anos - 30.11.2022 a 30.11.2024)

SILVA, Nuno - Development of zebrafish chemical screens to identify new modifiers of intestinal neutrophilic inflammation (embargo 1 ano - 18.02.2022 a 18.02.2023)

TEIXEIRA, Melissa - Nanoformulations of novel metal-complexes as potential antitumor agents (embargo 2 anos - 28.01.2022 a 28.01.2024)


Nutrição Humana e Metabolismo

CASTELA, Inês - Unravelling the role of adipose tissue metabolism in diet-induced weight loss : results from a randomised controlled trial (embargo 1 ano - 22.11.2022 a 22.11.2023)

LICKFOLD, Mafalda - Associação entre alterações da composição corporal e o perfil cardiometabólico após cirurgia metabólica e bariátrica

PITA, Débora - Portuguese questionnaires for assesing dietary supplements usage by athletes (embargo 2 anos - 04.04.2022 a 04.04.2024)

PROJECTO, Maria - The influence of anthocyanin treatment on the mesenteric adipose tissue expression of enampt in animal models of obesity

REMÍGIO, Inês - Associação entre o estado nutricional de indivíduos que tiveram diagnóstico de covid-19 e sintomas persistentes da doença

RODRIGUES, Tânia - The efficacy of faecal microbiota transplantation for the treatment of irritable bowel syndrome: a sistematic review and meta-analysis (embargo 1 ano 16.12.2022 a 16.12.2023)

SANTOS, Gilberto - Fecal samples with more bifidobacteria protect against intestinal permeability


Saúde Mental nos Cuidados Primários

MAHDY, Marwa - Assessment of Saudi public knowledge and attitudes toward mental health disorders and its demographic correlation (embargo 3 anos - 18.05.2022 a 18.05.2025)

Atualizado a 20 de fevereiro, 2024