NOVA Medical School | Faculdade de Ciências Médicas Rua Câmara Pestana n.º 6, lab 3.16 1150-082 Lisboa. PORTUGAL
Phone: +351 218803035 Ext: 26013

Sofia de Azeredo Pereira

Professor Professor Auxiliar

Prof Auxiliar & PI Translational Pharmacology Lab; Vice-Coordinator PhD Program in Biomedicine;  Member of Pedagogical Council; Coordinator of TDM  & Metabolomic Data Analyses Services

  • Correia MJ, Pimpão AB, Lopes-Coelho F, Sequeira CO, Coelho NR, Gonçalves-Dias C, Barouki R, Coumoul X, Serpa J, Morello J, Monteiro EC, Pereira SA. Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex. Antioxidants (Basel). 2021 Sep 17;10(9):1484. doi: 10.3390/antiox10091484.
  • Lopes-Coelho F, Martins F, Hipólito A, Mendes C, Sequeira CO, Pires RF, Almeida AM, Bonifácio VDB, Pereira SA, Serpa J. The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy. Front Oncol. 2021 May 10;11:656229. doi:10.3389/fonc.2021.656229. 
  • Marto N, Morello J, Antunes AMM, Azeredo S, Monteiro EC, Pereira SA. A simple method to measure sulfonation in man using paracetamol as probe drug.Sci Rep. 2021 Apr 27;11(1):9036. doi: 10.1038/s41598-021-88393-3.
  • Lopes-Coelho F, Martins F, Pereira SA, Serpa J. Anti-Angiogenic Therapy: Current Challenges and Future Perspectives. Int J Mol Sci. 2021 Apr 5;22(7):3765. doi: 10.3390/ijms22073765.PMID: 33916438 
  • Harjivan SG, Charneira C, Martins IL, Pereira SA, Espadas G, Sabidó E, Beland FA, Marques MM, Antunes AMM Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine. Molecules. 2021 Mar 3;26(5):1349. doi: 10.3390/molecules26051349.
  • Marinho AT, Batuca JR, Miranda JP, Caixas U, Dias CG, Branco T, Soto K, Pinheiro P, Bourbon M, Marques MM, Antunes AM, Monteiro EC, Pereira SA. The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies Pharmacol Res. 2021 Mar;165:105446. doi: 10.1016/j.phrs.2021.105446. 
  • Coelho NR, Matos C, Pimpão AB, Correia MJ, Sequeira CO, Morello J, Pereira SA*, Monteiro EC*. AHR canonical pathway: in vivo findings to support novel antihypertensive strategies. Pharmacol Res. 2021 Mar;165:105407. doi: 10.1016/j.phrs.2020.105407. 
  • Bonifácio VDB*, Pereira SA*, Serpa J*, Vicente JB* Cysteine metabolic circuitries: druggable targets in cancer. Br J Cancer. 2021 Mar;124(5):862-879. doi: 10.1038/s41416-020-01156-1. 
  • Gonçalves-Dias C, Sequeira CO, Vicente JB, Correia MJ, Coelho NR, Morello J, Antunes AMM, Soto K, Monteiro EC, Pereira SA. A Mechanistic-Based and Non-invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides. Adv Exp Med Biol. 2021;1306:109-120. doi: 10.1007/978-3-030-63908-2_8.
  • Coelho NR, Tomkiewicz C, Correia MJ, Gonçalves-Dias C, Barouki R, Pereira SA*, Coumoul X*, Monteiro EC*. First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia. Pharmacol Res. 2020 Sep;159:104869. doi: 10.1016/j.phrs.2020.104869
  • Gomes A, Godinho-Pereira J, Oudot C, Sequeira CO, Macià A, Carvalho F, Motilva MJ, Pereira SA, Matzapetakis M, Brenner C, Santos CN. Berry fruits modulate kidney dysfunction and urine metabolome in Dahl salt-sensitive rats. Free Radic Biol Med. 2020 Jul;154:119-131. doi: 10.1016/j.freeradbiomed.2020.05.002
  • Cipriano M, Pinheiro PF, Sequeira CO, Rodrigues JS, Oliveira NG, Antunes AMM, Castro M, Marques MM, Pereira SA, Miranda JP.Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model. Int J Mol Sci. 2020 Jun 3;21(11):3998. doi: 10.3390/ijms21113998.
  • Lopes-Coelho F, Silva F, Gouveia-Fernandes S, Martins C, Lopes N, Domingues G, Brito C, Almeida AM, Pereira SA, Serpa J. Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis. Cells. 2020 Jan 1;9(1):107. doi: 10.3390/cells9010107.
  • Best work submitted in Basic Nephrology Section Award awarded in 2021 Sociedade Portuguesa de Nefrologia
  • Best work submitted in Basic Nephrology Section Award awarded in 2017 Sociedade Portuguesa de Nefrologia    
  • Travel Grant. Thiol oxidation in toxicity and signaling workshop organized by EMBO. Award awarded in 2017

Ciência ID    6B13-7601-73A2