Rua Câmara Pestana, 6 1150-082 Lisboa
Phone: 218803100

Miguel Seabra

Professor Professor Catedrático
Principal Investigator

Miguel C Seabra, MD, PhD, is a leading researcher in the field of cellular and molecular medicine. MS holds a PhD from University of Texas Southwestern Medical Center (1992), where he was an Assistant Professor, before moving to the Faculty of Medicine, Imperial College London where he became Full Professor and head of Section until 2007.

MS is now Full Professor at the Medical School of the Universidade Nova de Lisboa, Portugal, where he coordinates research in Cellular and Molecular Medicine and holds several chairs. More recently, he became Head of Global Eye Initiative at Fundação Champalimaud. MS was president of Fundação para a Ciência e a Tecnologia (FCT) from 2012 to 2015, the portuguese public funding agency for science and research in Portugal.

  • Escrevente C, Falcão AS, Hall MJ, Lopes-da-Silva M, Antas P, Mesquita MM, Ferreira IS, Cardoso MH, Oliveira D, Fradinho AC, Ciossek T, Nicklin P, Futter CE, Tenreiro S, Seabra MC. 2021. Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction. Investigative Ophthalmology and Visual Science. 62:39. (IF: To be determined; Ophthalmology Q1).
  • Flores R, Carneiro A, Serra J, Gouveia N, Pereira T, Mendes JM, Coelho PS, Tenreiro S, Seabra MC. 2021. Correlation Study Between Drusen Morphology and Fundus Autofluorescence. Retina. 41:555–62 (IF: To be determined; Ophthalmology Q1
  • Xue K, JJolly JK, Barnard AR, Rudenko A, Salvetti AP, Patrício MI, Edwards TL, Groppe M, Orlans HO, Tolmachova T, Black GC, Webster AR, Lotery AJ, Holder GE, Downes SM, Seabra MC, MacLaren RE. "Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia". Nature Medicine 24 10 (2018): 1507-1512. http://dx.doi.org/10.1038/s41591-018-0185-5. (IF: 30.64; Multidisciplinary Q1).
  • Thieleke-Matos C, Lopes da Silva M, Cabrita-Santos L, Portal MD, Rodrigues IP, Zuzarte-Luis,V, Ramalho JS, Futter CE, Mota MM, Barral CD, Seabra MC. "Host cell autophagy contributes to Plasmodium liver development". Cellular Microbiology 18 3 (2015): 437-450. http://dx.doi.org/10.1111/cmi.12524. . (IF: 4.288; Microbiology (Q1); Immunology (Q2); Virology (Q2)).
  • MacLaren RE, Groppe M, Barnard AR, Cottriall CL, Tolmachova T, Seymour, L, Clark KR, During MJ, Cremers F, Black G, Lotery AJ, Downes SM, Webster AR, Seabra MC. "Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial". The Lancet 383 9923 (2014): 1129-1137. http://dx.doi.org/10.1016/s0140-6736(13)62117-0. (IF: 45.217; Medicine (miscellaneous) (Q1)).
  • Wavre-Shapton ST, Tolmachova T, Lopes da Silva M, Futter C, Seabra MC. "Conditional Ablation of the Choroideremia Gene Causes Age-Related Changes in Mouse Retinal Pigment Epithelium". PLoS ONE 8 2 (2013): e57769. http://dx.doi.org/10.1371/journal.pone.0057769. (IF: 3.534; Multidisciplinary Q1).
  • 2015 BIAL Grand Prix of Medicine, Portugal.
  • 2014 Gold Medal – Ministry of Health, Portugal.
  • 2012 Seeds of Science Prize, Portugal.
  • 2010 Jessie Mole Lecture, University of Oxford, UK.
  • 2006 Entrepreneurship Prize, Neotec, Innovation Agency, Portugal.
  • 1995-1999 Pew Scholar in the Biomedical Sciences, Pew Charitable Trusts, USA.
  • 1988-1993 Fulbright Program Scholar, United States Information Agency, USA.
  • 1988-1992 Postgraduate Fellowship, Fundação Calouste Gulbenkian, Portugal.
  • 1986-1988 Young Investigator Fellowship, INIC, Portugal
  • Ciência ID: 2512-FAEF-E26F
  • ResearcherID: M-3280-2013
  • Scopus Author ID: 7004369652