NOVA Medical School|Faculdade de Ciências Médicas Edífício CEDOC I Rua do Instituto Bacteriológico, n.ºs 5, 5-A e 5-B 1150-190 Lisboa PORTUGAL
Telefone: 218803000 Ext: 27015

Tiago Daniel Fidalgo Baptista

Investigador  Investigador Júnior
Tiago is a Junior Researcher at CEDOC|NMS, in the lab of Catarina Homem. His research focuses on the understanding of the molecular mechanisms in the interface between neural stem cell fate commitment, differentiation, and metabolism.
Baptista T, Devys D. Saccharomyces cerevisiae metabolic labeling with 4-thiouracil and quantification of newly-synthesized mRNA as a proxy for RNA polymerase II activity. JoVE. In press; Gupta K, Watson AA, Baptista T, Scheer E, Chamber AL, Koehler C, et al. Architecture of TAF11/TAF13/ TBP complex suggests novel regulation properties of general transcription factor TFIID. Elife. 2017; 6. dog: 10.7554/eLife.30395; Baptista T, Grünberg S, Minoungou N, Koster MJE, Timmers HTM, Hahn S, Devys D and Tora L. SAGA is a general cofactor for RNA Polymerase II transcription. Molecular Cell. 2017; 68(1):130-143. Warfield L*, Ramachandran S*, Baptista T, Devys D, Tora L and Hahn S. Transcription of nearly all yeast RNA Polymerase II-transcribed genes is dependent on transcription factor TFIID. Molecular cell. 2017;68(1):118-129. *contributed equally Junqueira-Neto S, Vieira FQ*, Montezuma D*, Costa NR, Antunes L, Baptista T, et al. Phenotypic impact of deregulated expression of class I histone deacetylases in urothelial cell carcinoma of the bladder. Molecular carcinogenesis. 2015;54(7):523-31. *contributed equally Almeida M, Costa VL, Costa NR, Ramalho-Carvalho J, Baptista T, Ribeiro FR, et al. Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential. Journal of cellular and molecular medicine. 2014;18(11):2287-97. Bonnet J*, Wang CY*, Baptista T, Vincent SD, Hsiao WC, Stierle M, et al. The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription. Genes & Development. 2014;28(18):1999-2012. *contributed equally Monteiro FL, Baptista T, Amado F, Vitorino R, Jerónimo C, Helguero LA. Expression and functionality of histone H2A variants in cancer. Oncotarget. 2014;5(11):3428-43. Graça I, Sousa EJ, Baptista T, Almeida M, Ramalho-Carvalho J, Palmeira C, et al. Anti- tumoral effect of the non-nucleoside DNMT inhibitor RG108 in human prostate cancer cells. Current pharmaceutical design. 2014;20(11):1803-11. Henrique R, Oliveira AI, Costa VL, Baptista T, Martins AT, Morais A, et al. Epigenetic regulation of MDR1 gene through post-translational histone modifications in prostate cancer. BMC genomics. 2013;14:898. Baptista T, Graça I, Sousa EJ, Oliveira AI, Costa NR, Costa-Pinheiro P, et al. Oncotarget. 2013;4(10):1673-85. Sousa E, Graça I, Baptista T, Vieira FQ, Palmeira C, Henrique R, et al. Enoxacin inhibits growth of prostate cancer cells and effectively restores microRNA processing. Epigenetics. 2013;8(5):548-58.
Principal investigator of one Exploratory Research Project (PeX) awarded by Fundação para a Ciência e a Tecnologia (FCT), Portugal, in 2021; CEEC Individual - Scientific Employment Stimulus 1st edition, Junior Researcher Position, awarded by Fundação para a Ciência e a Tecnologia (FCT), Portugal, in 2019; Long-term Fellowship, awarded by European Molecular Biology Organization (EMBO), in 2018; 4th Year PhD fellowship awarded by Fondation ARC pour la Recherche sur Le Cancer, France, in 2016; Marie Curie - Initial Training Network PhD fellowship awarded in 2013; Grant to initiation in research awarded by Fundação para a Ciência e a Tecnologia (FCT), Portugal, in 2009.
ORCID: 0000-0003-3196-8308 Ciência ID: F81E-5F8C-BBC4